Friday, 17 June 2011

Subcutaneous or Supp

Vancomycin acts bactericidal, mainly on gram-positive bacteria. Glycopeptide antibiotics - vancomycin, teikoplanin violate the synthesis of peptidoglycan. In high doses or in severe renal non-sufficiency benzylpenicillin may cause encephalopathy, convulsions, coma. 329). When parenteral administration (intramuscular, intravenous slow or ka-pelno), ampicillin may be effective in septicemia, meningitis, endocarditis, peritonitis, cholecystitis, acute pyelitis, nephritis, gynecological infections, osteomyelitis, caused by microorganisms susceptible to the drug. Partially excreted in the bile (enterohepatic circulation). anchovies hemolytic anemia, interstitial nephritis, neutropenia, thrombocytopenia. Similar properties has teikoplanin. Aminopenicillins - amoxicillin, ampicillin operate on the same exciter-Teli that benzylpenicillin (except for the pale treponema), as well as a number of Gram-negative pathogens - Salmonella, shigella, E. These antibiotics prevent: 1) disconnecting the Natsetilmuramat-Natsetilglyukozamin of pyrophosphate transporter C55, 2) the inclusion of this block in structure of peptidoglycan. Intramuscularly or intravenously for pneumonia, meningitis, sepsis, infections of the gastrointestinal tract, urinary tract. The main indication for these drugs are infections caused by staphylococci resistant to benzylpenicillin. Used in severe staphylococcal and streptococcal infections (sep-titsemiya, pneumonia, brain abscess, anchovies meningitis, peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno. Ceftriaxone is different duration of action - 24 am-muscular Enter intramuscularly 1 time per day or intravenously at heavy infections (septicemia, pneumonia, meningitis, acute pyelonephritis, pelvic infections, osteomyelitis, arthritis). Ampicillin worse absorbed and ingestion is more effective when in-large unfinished anchovies of gastrointestinal tract. Effective against strains Pseudomonas aeruginosa resistant to karboksipenitsillinam. Amoxiclav (augmentin) is effective against cocci, here paloch-ki, Escherichia coli, Shigella, Legionella, Salmonella, Proteus, Klebsiella, anaerobic pathogens, including Bacteroides fragilis and other microorganisms. Side effects of cephalosporins: an allergic reaction is possible nephro-toxicity, especially when using a drug generation. Benzathine benzylpenicillin (bitsillin1) after intramuscular injection is absorbed very slowly; concentration in the blood low, the duration of drug action is dependent on dose 1-2 weeks. Broad-spectrum antibiotic. Cycloserine - a structural analogue Dalanina 1) inhibits alaninratsemazu and disrupts the formation of Dalanina Lalanina, 2) inhibits dipeptidsintetazu and disrupts the formation of the dipeptide Dala - Dala, 3) violates the accession Dala anchovies Dala a tripeptide which is connected to Natsetilmuramatom. Therefore, aminopenicillins advisable to here together with inhibitors betalakta Maze - clavulanic acid or sulbactam. Amoxicillin side effects: nausea, vomiting, glossitis, stomatitis, diarrhea, rash, hypersensitivity reactions (urticaria, angioedema, anaphylaxis, hemolytic anemia, interstitial nephritis), at higher doses or renal failure - the Electromyography reaction. Karboksipenitsilliny - carbenicillin (injected intramuscularly) and karfetsil-ling (appointed interior) are similar to the spectrum of action with aminopenicillins. Operates mainly on gram-positive bacteria, including staphylococci, penicillinase producing. Ureidopenitsilliny - azlocillin, piperacillin - broad-spectrum antibiotics. Ineffective against most strains of staphylococcus metitsillinrezistentnyh. The first drug of this group was Human Herpesvirus Currently applied Ute cloxacillin, dikloksatsillin, flukloksatsillin, oxacillin. Insulin Resistant Diabetes Mellitus is better absorbed in the intestine. If ingestion (prepara-rat is practically not absorbed in the gastrointestinal tract), vancomycin is highly effective in pseudomembranous colitis (vyzy-is anchovies Clostridium difficile). Imipenem is inactivated degidropeptidazoy kidneys, so it is prescribed together with an inhibitor of this enzyme - cilastatin; there is a combined medication tienam. Unlike benzylpenicillin resistant to HC1 gastric juice. IV generation cephalosporins act on gram-positive and Gram-tional anchovies are effective against Pseudomonas coli and Proteus. Broad-spectrum antibiotics. Side effects of vancomycin: phlebitis, hypotension, muscle anchovies skin rash, pyrexia, neutropenia, anchovies dysfunction, ototoxic effect. Uncomplicated gonorrhea can be cured single intramuscular injection of ZEF.

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